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This retrospective analysis of burn patients in a University Hospital in the state of Sao Paulo, Brazil, was carried out to characterize this population and to identify the factors that affect the mortality rate. All patients hospitalized from January 1990 to April 1995 (n = 229, 3.6 patients/month) and who terminated treatment were included. Of these, 80.8% (185 patients) were hospitalized within...
We investigated nitric oxide and cyclic GMP production in myocardium early after burn injury in rats. Nitric oxide synthase activity was measured in cytosol from the left ventricular wall of burned rats. Cytosol from control group animals was shown to contain mainly Ca 2+ -dependent nitric oxide synthase (cNOS) with a small amount of Ca 2+ -independent nitric oxide synthase...
The purpose of this study was to assess the reaction to burn trauma, the hospitalisation characteristics and psychosocial adjustment in 174 burn victims who agreed to participate in a structured interview. It was postulated that once patients sustain a burn, the level of loneliness feelings and feelings of shame is a function of the visibility of the scars. Contrary to expectation, the visibility...
It goes without saying that pain following a burn must be treated but it is not so evident to measure and document the intensity of pain and the efficacy of treatment. Since 1994 the authors have routinely measured background pain, that is, at rest, along with temperature and pulse rate. For analysis and quality assessment a relational database programme is used in the ward. In this paper the authors'...
A wide range of drugs are capable of being administered as transdermal drug delivery systems (TDDS). Despite their advantages, these systems are known to have adverse effects. This report describes localised skin reactions with reference to a burn-like lesion on the shoulder of a patient caused by a testosterone TDDS. Patients should be advised of the potential adverse effects of these systems...
Progressive burn wound necrosis is an important factor as a cause of delayed healing during clinical therapy of burns. Among the causes of progressive necrosis have been attributed an insufficient blood supply or a dehydration at the zone of stasis just beneath the zone of coagulation. In a previous study evidence was presented that hypernatremia, an osmotic injury, may act to promote progressive...
The purpose of this study was to examine the relationship between psychosocial adjustment of the burned child and characteristics of the child's family. It hypothesized that parents who perceived their children without major behavioural problems would possess supportive family values and would, themselves, be better adjusted psychologically than those parents who perceived their children as possessing...
Gasoline is intended for use as a motor fuel, but the universal availability of gasoline in the home encourages misuse as a solvent, insecticide, accelerant or cleaning solution. The careless or inappropriate use of gasoline may result in burn injury. We examined the circumstance of gasoline-related injury in a population admitted to one burn centre to determine the potential for burn prevention...
Electrical kettles (el-kettles) were virtually unknown in Danish households in the mid-1980s, but have since become more common. In 1996, 65 per cent of all Danish households had an el-kettle. As the number of el-kettles have increased, so have the number of scalds caused by water from toppled el-kettles. The first patient with an el-kettle scald was admitted to the Burns Centre at Hvidovre hospital...
The successful use of elective post-operative sedation and ventilation following tangential surgical excision of burns in an autistic child, non-compliant with conventional management is reported. Other strategies for treating autistic children are discussed.
A case of severe electric burns complicated by multiple antibiotic resistant Pseudomonas aeruginosa not responding to various antibiotics administered systemically is presented. Citric acid (3%) was used successfully to eliminate Pseudomonas aeruginosa from burn wounds and infection was completely controlled in 14 days. Citric acid treatment is evidently of value in the clinical control of burn...
Introduction: The effect of burns surgery that requires intraoperative transfusion of five or more units of blood on serum vancomycin levels was assessed. Methods: Serum vancomycin levels were measured 10 min and 6 h after vancomycin administration with surgery being performed in the interval. The following day the same dose of vancomycin was given and serum vancomycin levels measured at the same...
Previous research aimed at identifying factors that increase the risk of major burns patients experiencing psychological problems post-burn has generally ignored the potential role of psychological factors. In a prospective study, patients with burn injuries ranging from <1 per cent up to 40 per cent were interviewed within 2 weeks of sustaining the burn and followed up at ca 3 months post-burn...
Industrial burn injuries result in significant morbidity, infrequent mortality and man-hour loss, leading to loss of productivity. With a view to study the epidemiology of industrial burns in Jamshedpur and first aid awareness, we analysed 815 patients (142 inpatients and 673 outpatients) with industrial burns seen by us during the period from January 1993 to December 1996. 69% of these injuries...
An unusual pattern of hypopigmentation along the proximal veins following repeated intralesional injection of triamcinolone acetonide in a keloid over the left shoulder of a 14 year old girl is reported and the relevant literature is reviewed.
The objectives of this study were to verify which circumstances are present in burn accidents of patients under 12 years of age and to gather information to ground strategies to prevent those accidents. Parents or guardians of 26 patients aged under 12 years, admitted to the burns unit of the Clinical Hospital of Ribeirao Preto Medical School, Brazil, were interviewed, from March 1996 to March 1997...
The anti-inflammatory agent D-myo-inositol-1,2,6-trisphosphate (1,2,6-IP 3 ) has shown beneficial effects in experimental burns following systemic administration. The purpose of this study was to investigate the effect of topical 1,2,6-IP 3 cream on a standardised full-thickness 1 cm 2 burn injury in rats. The experimental cream contained a transcutaneous absorption enhancer,...
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